Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. Reprinted material is quoted with permission, and sources are indicated. Government works Printed in the United States of America on acid-free paper 10 9 8 7 6 5 4 3 2 1 International Standard Book Number-10: 0-8493-3858-1 (Hardcover) International Standard Book Number-13: 978-0-8493-3858-8 (Hardcover) Library of Congress Card Number 2006040380 This book contains information obtained from authentic and highly regarded sources. Informa Healthcare is an Informa business No claim to original U.S. 270 Madison Avenue New York, NY 10016 © 2006 by Informa Healthcare USA, Inc. Keller Toxicology Consultant Washington, D.C., U.S.A. Food and Drug Administration Silver Spring, Maryland, U.S.A. Toxicological Testing Handbook Principles, Applications, and Data Interpretationĭavid Jacobson-Kram U.S.
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